Murray has quietly rushed for the fourth-most yards of any running back in the NFL in 2015, and he's accounted for five touchdowns on the ground. His ability to give the Raiders a balanced offense has made Oakland's passing attack more dangerous.
Marshall, the Broncos' leading tackler, will be without his usual inside linebacker partner, Danny Trevathan. In Trevathan's stead, Marshall will move into his spot, leaving Marshall's normal "mike" linebacker position to reserve Todd Davis.
Whether Marshall and Davis can keep Murray from reaching the second level for much of the day could dictate what the Raiders can do offensively.